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More recently, another microbial product, p-cresol, a glucuronide, has been found to decrease permeability of the BBB in vitro and has protective effects over LPS induced BBB disruption in mice [156]

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The peptide's pharmacokinetics in dogs absorption, half-life, and clearance have not been characterized, so neither dosing frequency nor the ideal timing of administration relative to an injury is known

Results and discussion This section presents the results and discussion of the study, which focuses on predicting the solubility of rivaroxaban, a poorly water-soluble anticoagulant, in mixed solvent systems