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Polymeric nanoparticles, such as those generated from polylactic-co-glycolic acid (PLGA) or polyethylenimine (PEI), also appear promising, as these materials can be tailored to deliver siRNA precisely to microglia or neurons while allowing for prolonged release (96)

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TABLE 1 Overview of the literature investigating microplastics (MPs) exposure in different samples of the human body

This is also consistent with our MALDI PFC imaging results showing reduced GABA and increased DA expression