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Gastroenterology 2016;150:1160-1170.e3

J Biol Chem 286:2991329921

Altered scavenger receptor expression and response to oxidative stress is linked to defective bacterial phagocytosis in COPD macrophages

Moreover, SCFAskey metabolites of the gut microbiotaregulate mucus dynamics, stimulating mucin secretion at low concentrations but potentially suppressing it at higher levels (6668)

Reactive oxygen species (ROS) consist of reactive species like superoxide (O 2 ) and hydroxyl radical (HO), along with nonradical species such as hydrogen peroxide (H 2 O 2 )