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To investigate whether the rescue effect by the drugs is associated with AMPK pathway, we examined the expression levels of AMPK and downstream mTOR pathway markers using RT-qPCR in the LMNA mutant transgenic fish with or without treatment

Therapeutic neural exosomes can deliver diverse therapeutic cargo (nucleic acids, proteins, lipids, and small-molecule drugs), enabling synergistic multi-targeted interventions (Di et al

Research has also shown that, in hypothyroid patients, there was indeed a trend for muscle carnitine content to be lower than normal, and that carnitine levels improved with thyroid hormone treatment

Based on identification of LV myocardium, the part of the basal slice belonging to the LV was included, and the LV outflow tract was included based on reference to the 3-chamber image 10

analyzed 50 CSF samples from patients with AD-like pathology defined by decreased A42 and increased t-tau and p-tau CSF levels (60)