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J Exp Bot 75(9):26042630

10.1038/s41419-023-05859-0 274 ZhangT.BaiS.DingX.ZengQ.XuanY.XuS.et al (2024)

Free-radical ROS includes superoxide anion radical (O 2 ), hydroxyl radical (OH), peroxyl radical (ROO), and sulfhydryl peroxyl radical (RSOO)

However, some clinical studies have reported that minocycline does not significantly improve symptoms in patients with depression or bipolar disorder (121)