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A total of 74 and 55, from a total repertoire of 1000, of the antibody spots were positive on initial screening using cell lysates or conditioned media respectively

This could be reversed by immune suppression with a combination of dexamethasone and cyclosporin A suggesting an antitumorous effect of O(3)/O(2)-mediated activation of the bodys own immunosurveillance

*Correspondence: Pan Tingting, [email protected]

An overview of recent developments in the field of nanoparticle-mediated CNS drug delivery and a brief discussion of significant hurdles to drug delivery to the CNS and the progress made so far in overcoming such hurdles for traditional CNS therapies have been attempted here

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