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In PtGSTU19Y160F variant, the apparent affinity for glutathione was reduced by a factor 4 with PITC as electrophilic substrate while no variation was detected with BITC

12 MorrisD.GuerraC.DonohueC.OhH.KhurasanyM.VenketaramanV

Amsterdam, the Netherlands: Elsevier

These haptenated HLA-B*57:01 bound peptides were displayed (i) through antigen processing of flucloxacillin-modified intracellular proteins, and (ii) direct binding of flucloxacillin to peptides already displayed by B*57:01 on the surface of antigen presenting cells