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In the present review, we describe homocysteine metabolism and its regulation by tissue folate and S-adenosylmethionine levels

Oral bioavailability and BBB permeability: CSF1Ri compounds exhibit good oral activity and brain penetration, enabling long-term and reversible microglial depletion, which facilitates in-depth studies of microglial roles in neurodevelopment, homeostasis, and disease

Large-scale clinical studies are needed before definitive conclusions can be drawn

SMA-positivity was associated with improved long-term cancer survival, though further studies are needed to investigate this effect

De novo NAD+ synthesis contributes to CD8+ T cell metabolic fitness and antitumor function