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Gpx4 fl/wt LysMCre + mice also displayed SLE-like clinical manifestations, including alopecia, lymphadenopathy, splenomegaly, proteinuria, significant increases in anti-dsDNA antibodies, IFN-, IL-6, and decreased complement C3 levels, indicating a close association between decreased neutrophil GPX4 protein expression and SLE pathogenesis

If your body cant absorb the vitamin through food and starts showing the symptoms of deficiency, your doctor might prescribe vitamin B12 shots

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