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Ltd, Tokyo, Japan) equipped with a Peltier-controlled cell holder (model PTC-517, JASCO)

Overall, we evaluate whether these disease-modifying emerging therapeutics hold promise as interventions that may be able to reverse or halt AD progression

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For example, mutant p53 can induce noncanonical NFB (NCNFB) signaling through the cGASSTING pathway, which promotes tumor cell invasion, metastasis, and immunosuppression

Membrane disruption and lipid peroxidation: the cell membrane is a primary target