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The deregulation of respiratory chain enzymes firstly decreases ATP synthesis and secondly overproduces ROS, which cannot be neutralized by the cell

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For the group fed 126ppm in their food an increased lifespan and healthspan was noted in both male and female mice without overt detrimental side effects as noted in the injection group

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Evaluation of antioxidant systems (coenzyme Q10 and total antioxidant capacity) in morbid obesity before and after biliopancreatic diversion