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However, in contrast to these techniques, which could also utilize intracellular transport of olfactory axons and extracellular transport processes along the olfactory nerve and the trigeminal nerve, mitochondria could only be delivered via the extracellular pathway to enter the AOB (since no significant presence of mitochondria was observed in olfactory neurons and the olfactory-trigeminal pathway, even after long-term treatments) and then reached the basal ganglia of the forebrain and lateral ventricles through the RMS pathway

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