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They are simply maintaining exogenous testosterone rather than cycling on and off

The severity of schizophrenia depends in part on oxidative stress and the level of neurochemical imbalance affecting neural circuits in several brain structures such as the hippocampus, prefrontal cortex, and striatum (18, 57)

Cancer Med (2023) 12(1):719

Cureus 16 , e69113 (2024)

In order to produce a pharmacological effect, a drug needs to cross the bloodbrain barrier (BBB) in sufficient concentration and interact with a target within the brain