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mGSH acts in concert with other antioxidant enzymes such as GPx1 and GPx4, GSTs, glutaredoxin-2, and ATP binding cassette transporters to maintain mitochondrial function [26,27]

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Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

Teicher BA, Fricker SP

Testing for GST mutations can provide important information for risk assessment and personalized treatment strategies in a variety of clinical settings