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[PMC free article: PMC1999396] [PubMed: 17911242] 148

Four patients who were non-responsive to propranolol were treated with topiramate, and all of them had a satisfactory response

46,112 Furthermore, McDermott et al 115 have shown that patients who walk more (3 times weekly) experience a slower rate of functional decline within the next year

However, because there are more than 60 KGDDs, there is a strong likelihood that changes in KG abundance also affect DNA-repair processes through other mechanisms