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Reconstitution technique matters

The actin-binding region itself has been linked to vascular activity: a 2003 study in the FASEB Journal reported that the site promoting actin interaction is also associated with angiogenic activity in experimental models

Ad-p53 Gene Therapy for Lung Cancer, Best of ASCO, CD Rom, 2001

In contrast, further studies showed that the density of MOR-like immunoreactivity is significantly reduced in the ipsilateral dorsal horn (laminae I and II) L4/5 segment after L4/5 SNL in SD rats [99], and similar studies have found that the expression of MOR protein in the L4/5 spinal cord segment decreased from the 35th day of ligation in the L5 SNL model of rats [100]

[PubMed] [Google Scholar] 214.Das SK, Eder S, Schauer S, Diwoky C, Temmel H, Guertl B, et al