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2019;39(4):BSR20181709

Stimulating Dermal Papilla Cell Proliferation The dermal papilla is the command center of the hair follicle a specialized cluster of mesenchymal cells at the base of the follicle that signals to the surrounding matrix cells to produce hair

Arrowheads indicate iron-dense granules

As PINK1 stabilizes on the MOM and autophosphorylates, it influences Parkin by phosphorylating pre-existing ubiquitin molecules already conjugated to MOM proteins at Ser65 [48], by phosphorylating pSer65-Ub-bound Parkin [44], or by directly phosphorylating the Parkin in the absence of its initial encounter with pSer65-Ub [44, 49, 50]

Biocyte