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Discovery and pharmacological characterization of JNJ-64619178, a novel small-molecule inhibitor of PRMT5 with potent antitumor activity

Conflict of interest The authors report no conflicts of interest

The effect of acylcarnitine on insulin sensitivity is also related to the saturation of acylcarnitine, with myotubes incubated with C16-carnitine exhibiting reduced insulin sensitization, whereas the accumulation of oleoylcarnitine (C18:1-carnitine) and linoleoylcarnitine (C18:2-carnitine) increases insulin sensitization [77]