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Aging, smoking, infection, genetic predisposition, abnormal biomechanical loading (such as long-term bending or heavy lifting), and reduced nutrient supply through the cartilage endplate are all inducing factors (Wu et al., 2021)

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You may also develop weakness or numbness in the leg for a few hours

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Muscle preservation & physical performance models

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All cited findings remain pre-clinical or limited cosmetic-research data

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Annu Rev Pathol 2010;5, 99118, doi: Herbig, U., Ferreira, M., Condel, L., Carey, D

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