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nci Turkoglu, orcid.org/0000-0001-8401-962X

Conclusions Based on the available evidence, the primary drivers of IR are metabolic disturbances in insulin-responsive tissues (liver, skeletal muscle, and adipose tissue) and impaired insulin production by -cells at the stage of T2DM

& Borgdorff, M

While it was previously believed that carriers of germline pathogenic PMS2 variants represented a small minority of LS patients, recent studies have challenged this assumption