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Extensive evidence suggests that adiponectin plays an anti-inflammatory role by modulating macrophage proliferation and polarization (115118)

[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Hanschmann E.M., Godoy J.R., Berndt C., Hudemann C., Lillig C.H

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This might indicate that GS - , which is displaced upon intramolecular disulfide formation, stays associated with the scaffold site kinetically facilitating the back reaction towards the glutathionylated state