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The clinical evidence for Rhodiola rosea is supported by multiple randomized, double-blind, placebo-controlled trials, including a phase III study evaluating the standardized extract SHR-5, which demonstrated statistically significant improvements in depressive symptoms with a favorable tolerability profile

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Published by Cambridge University Press on behalf of the Nutrition Society A key hallmark of ageing is increased oxidative stress (Reference Hekimi, Lapointe and Wen1)