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Specifically, SIRT3 inhibition suppresses fatty acid oxidation, causing reduction of OXPHOS and ATP level, which leads to LSCs vulnerability to lipotoxicity (176)

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CB was directly loaded without solution adjustment at 150200-CVs followed by 810-CV of wash 1 buffer at 300400 mM NaCl or the indicated NaCl concentration gradient and 45-CVs of wash 2 buffer at 75100 mM NaCl and 1 mM DTT

Consistently, mice deficient for PKD3 in hepatocytes presented lower glucose levels when fasted for a prolonged period (Fig 5H)

Fermentation 6(4):106