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The standard uptake value in 18 F-fluorodeoxyglucose (FDG) PET has been associated with histopathologic grade, cellularity, mitotic activity, MIB-1 labeling index, and TP53 overexpression, but it has never been proven to provide independent prognostic information and frequently fails to distinguish benign tumors from low-grade sarcomas

Recent studies describe interesting interplays between parkin oxidative modifications, its role in mitochondrial quality control and PD onset (Zhang et al., 2016)