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Mycopathologia 161 , 225228 (2006)

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A small-molecule epigenetic-silencing-inhibitor was identified to enhance myelin production and ensheathment, highlighting the potential promise of pharmacological intervention for promoting remyelination

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Agios Pharmaceuticals ivosidenib (Tibsovo) targets these mutations and has received FDA approval to treat AML and cholangiocarcinoma with IDH1 mutations