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10.1161/circulationaha.105.551457 Circulation 63 LiedtkeA

If redness or stinging occurs, discontinue use and try again another day with fewer pumps and more resting time

Unlike its parent molecule EPO, ARA-290 selectively activates tissue repair mechanisms without stimulating erythropoiesis, offering a potentially safer therapeutic profile

Cases with former or planned knee-joint replacement, being under pharmacologic treatment for obesity, having no history of or active rheumatic diseases, using no nonsteroidal anti-inflammatory drug (NSAID), consuming multivitamin, minerals or other nutritional supplements, and having severe liver, kidney, or heart diseases were excluded from the study