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Nematode-derived immunomodulatory molecules include mimics of host immune mediators as well as novel molecules that are unique to parasites themselves

1 2 "The global burden of suicide mortality among people on the autism spectrum: A systematic review, meta-analysis, and extension of estimates from the Global Burden of Disease Study 2021"

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Cluster analysis (Figure S5B) demonstrated clear separation between groups: controls clustered with high Bacteroidota/Actinomycetota representation, ASD models formed a distinct Firmicutes-dominated cluster, and hCiPSCs-treated animals occupied an intermediate position

The FSP1-CoQ10-NAD(P)H pathway exists as an independent parallel system, compatible with GPX4, and works with glutathione to inhibit phospholipid peroxidation and ferroptosis