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CAGE transcriptome analysis reveals BCL2A1 upregulation in FLT3-ITD/D835 dual mutated AML cells harboring complex co-mutations

Considering the newly identified role of amino acid metabolism in macrophage polarization, we are optimistic that exploiting NMs to regulate amino acid metabolism within macrophages to emerge the desired phenotype will be a new research direction, although the blueprint is premature

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Interaction of Au 15 SG 12 -Ao with protein carbonyls Since protein carbonylation occurs on solvent-exposed amino acids, we predicted that Au 15 SG 12 - Ao would react with carbonylated proteins through the formation of an extremely stable oxime bond between the amino group of the Ao attached to the NC and carbonyl groups on the amino acids (Fig

Combined these findings suggest that Ru(II)-OH could efficiently and catalytically oxidize GSH to GSSG