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Lein ES, Hawrylycz MJ, Ao N, Ayres M, Bensinger A, Bernard A, et al

However, when oxidative stress becomes too high due to external factors like UV rays or processed foods, it can lead to cellular fatigue

For G protein and -arrestin2 receptor recruitment studies, we used human G i1 with nanoluciferase (NanoLuc) inserted at position 91 (NanoLuc-G i1(91) ) and human -arrestin2 fused with NanoLuc at the N terminus (NanoLuc--arrestin2)