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MTX is mostly taken up by cells via the SLC superfamily of transporters such as SLC19A1, SLC21, SLC22, and SLC46A and can be pumped out by different ABC (Desmoulin et al

The licensed NAC oral dose of 600 mg/day appears to be sufficient for preventing COPD exacerbations, although patients presenting with airway obstruction may benefit from doses 1200 mg/day

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Abiotic stressors such as cold, drought, heat, salinity, and flooding negatively impact plant growth and productivity, causing various physiological, morphological, molecular, and biochemical changes ( Figure 1 ) (Popp et al., 2013)