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These pathological changes enhance the systemic translocation of luminal bacteria, some of which provide mimotopes or augment autoimmune responses ( Figure 1 )

Consequently, vitamin B 12 deficiency rarely occurs before the infant is about 4 months old if the mother has adequate vitamin B 12 status during pregnancy

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While surviving longer than tropical populations, temperate populations were nonetheless likely to face extinction ( From these and similar studies, a mixed picture emerges

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