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They also accumulate very high levels of 18:0 (Figure 7B)

Recent studies have highlighted the potential of statin use in reducing the incidence of diverse cancers, potentially achieved through YAP/TAZ suppression via the mevalonate pathway inhibition in vitro

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[PMC free article: PMC5047290] [PubMed: 26361259] 235

In summary: SAG provides direct, synthesis-independent intracellular GSH delivery, making it particularly suited for research models where the GSH synthesis pathway may be compromised or where researchers require rapid, direct intracellular GSH loading