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We demonstrated that this mutant is retained in the ER and degraded via the ER-associated degradation (ERAD) pathway

Accuracy of data collection To ensure accuracy of search results and to reduce potential errors due to manual collection, screening for eligibility, data extraction, and quality assessment were done in duplicates and cross-matched in each subgroup

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Osborne CK, Monaco ME, Kahn CR, Huff K, Bronzert D, Lippman ME

DCs are directly or indirectly involved in the development of RA, and interactions between DCs and Tregs also interfere with RA development