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Oxidative stress, compounded by mitochondrial dysfunction and NADPH oxidase activation, damages cardiac myocytes, leading to arrhythmias and impaired ventricular function, while the formation of ONOO further disrupts cardiac contractility (117)

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Neither the degree of flushing nor the rate at which it occurs necessarily correlate to ones level of alcohol intoxication

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

Chronic alcohol metabolism results in DNA repair infidelity and cell cycle-induced senescence in neurons