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However, HIF-1 alone is insufficient to achieve the complete program of adaptive changes required for cell survival under hypoxic stress, while the unfolded protein response (UPR) responding to endoplasmic reticulum stress plays an essential supplementary role in promoting cell survival

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This maternal mode of transmission provides the biological basis for maternal co-inheritance, linking the inheritance of mtDNA with the transfer of a maternally established mitochondrial regulatory context [20]

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Mast cells are a part of our innate immune system and are vital to our bodys response to invaders