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Silencing of either SR-A or CD36 reduces atherosclerosis in hyperlipidaemic mice and reveals reciprocal upregulation of these receptors

Although glutamate is the major downstream product of glutamine, glutamate supplementation during glutamine deprivation cannot rescue the impaired cell growth or mitochondrial respiration 16,43,44,45 , indicating that mitochondrial GLS-catalyzed cleavage of the gamma-nitrogen of glutamine is essential for glutaminolysis

View Abstract Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism

Mitochondrial dysfunction in DN is often linked to increased production of ROS, which can lead to oxidative damage and impaired energy metabolism

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