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Mitochondria-targeted pentacyclic triterpenoid carbon dots for selective cancer cell destruction via inducing autophagy, apoptosis, as well as ferroptosis

In the gastric cancer TME, L-Kynurenine (L-KYN), which is a metabolite derived from tryptophan, was documented to provoke lipid peroxidation thereby induce ferroptosis in NK cells [135]

Quercetin is an important flavonoid with a variety of protective properties, it has been shown that quercetin inhibits ferroptosis in renal tubular epithelial cells by activating the HO-1 signaling pathway to regulate the expression level of antioxidant enzymes and by reducing intracellular ROS production and iron overloading [77]

[DOI] [PMC free article] [PubMed] [Google Scholar] 222

Promotes cell renewal and improves skin texture