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PubMed Abstract | Publisher Full Text 298

Metformin also modulates other critical pathways, dampening integrin/ERK signaling, limiting matrix-degrading enzymes, and protecting enlarged fat cells from premature death (334)

The rise in Bcl-2-associated X protein (BAX) expression and the activation of cleaved poly (ADP-ribose) polymerase and caspase-3 generated by hyperosmolarity were mitigated in a concentration-dependent manner by P