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Description

E.Sanchez-SantosM

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RRID: SCR_008452)

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This study systematically reviews the most recent advancements in HGSOC drug resistance research, concentrating on the molecular biological foundations of resistance mechanisms, innovative detection strategies, and potential therapeutic approaches

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Specifically, it hinders the activation of protein PKC in response to mitogens, as zinc deficiency prevents PKCs translocation to the cell membrane

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In addition to transcription factors mentioned above, there are also some other mechanisms involved in sorafenib resistance

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