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Similarly, IL-1-induced BMSC-Exos reversed hemin-induced ferroptosis in neuronal cells, including high iron, ROS, malondialdehyde (MDA), 4-hydroxynonenal (4-HNE), and reduced GSH level and cell viability [143]

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Pre-dissolution in purified water before incorporation ensures even distribution throughout formulations while avoiding localized concentration hot spots that may affect product consistency

10.1016/j.ebiom.2019.05.064 6 AitbaliY.Ba-M'hamedS.ElhidarN.NafisA.SoraaN.BennisM