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-amyloid fibrils in alzheimer disease are not inert when bound to copper ions but can degrade hydrogen peroxide and generate reactive oxygen species

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Biol Blood Marrow Transplant 14 (9 Suppl): 16-22, 2008

Although both oxidized and antioxidant levels of lipids are higher in RA-FLS than in healthy controls, the increase in antioxidant levels is slightly higher than that of oxidation, indicating that RA-FLS is resistant to ferroptosis ( + T-cells from ferroptosis ( In studying TNF-, an important inflammatory mediator in the pathogenesis of RA, it was found that small doses of TNF- could enhance Cys uptake and GSH synthesis by activating the NF-B pathway