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28 In addition, homocysteine is known to cause endothelial (protective lining) damage, a recognized contributor to the progressive loss of kidney function

Journal of Biological Chemistry , 294 (13), 4924

& Colonna, M

In addition to JPH-203, other drugs currently in preclinical and clinical trials targeting LAT1 include IPA-131, QBS-10072S, TLX101-CDx, 124I-ACD-101, 211At-TLX-102, OKY-034, [18F] NKO-028 (Table 1)