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Indeed, evidence suggests that the clearance of TPO-Ab seems to occur in parallel with other immunologic mediators such as interferon-, TNF-, interleukin-1, and interleukin-2, as well as C-reactive protein (54, 55) which might explain the benefit of the complete removal of the antigenic tissue via total thyroidectomy

Pickles et al., 2013, 2016

Regarding the latter application, some clinical investigations reported that non-alcoholic fatty liver disease (NAFLD), the most common chronic liver disease worldwide ( 32 ), could favor APAP-induced AFL after an overdose ( 33, 34 )