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Moreover, it has been shown that hyperuricemia (also observed in our study) can cause significant changes in systemic and renal hemodynamics, which may result in the loss of autoregulatory kidneys function 54

The recently emerging reverse transcriptase (RT-) editors are gene editing tools that can introduce all types of point mutations, small insertions, and deletions without double-strand breaks or DNA donor templates

The deproteinized samples were incubated with necessary reaction components for 30 min at room temperature protected from light

PA: Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing original draft, Writing review & editing