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Notably, further studies discovered an inducible GPX4 transcript-variant (iGPX4) in NAFLD conditions, and suppression of iGPX4 by siRNA-iGPX4 significantly alleviated oxidative stress and cellular damage by impairing ferroptosis

Here the committee briefly reviews several of the most commonly used animal models of TBI (Morales et al., 2005): the weight-drop model, the controlled cortical impact model, the fluid percussion model, and the impact acceleration model (Figure 3-2)