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These methodologies collectively provide a robust foundation for targeting ferroptosis in both basic research and translational medicine

The Cytochrome P450 monooxygenase system (CYP) is a crucial pathway in this regard

Across most of the outcome measures analysed, cuprizone pellets were generally better than cuprizone powder at inducing early demyelinating disease pathology compared to their relative controls, particularly in the caudal corpus callosum (Table 1)