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Yale Surgery Project Showcase, 2024

10.3389/fphar.2022.966645 135 WangY.YouK.YouY.LiQ.FengG.NiJ.et al (2022d)

Glucose metabolism disruptions occur not only in pathology but also with aging, marked by metabolic abnormalities and bioenergetic dysregulation [72]

however, in CKD, impaired renal function leads to systemic phosphate accumulation, driving its pathogenic effects (Lang E

Moreover, the authors highlighted phenoconversionthe modulation of metabolic activity by external factors such as drug-drug interactionsas a critical complicating variable