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Neurotoxicity of manganese via ferroptosis induced by redox imbalance and iron overload

In Huntingtons disease (HD), oxidative stress plays a significant role in the neurodegenerative process

Genomics 6 , 103111 (2005)

In STAT3-knockdown MCECs (siSTAT3-transfected), GHK-Cu failed to enhance wound healing in scratch assays (Figures 7A,B) and did not upregulate ZO-1/Occludin expression (Figures 7CF)