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X-box binding protein 1 (XBP-1) is a transcription factor that promotes XBP-1 expression

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Since drastic depletion of the patrolling monocytes subset along with increased levels of classical/inflammatory CD14 high CD16 monocytes were observed in COVID-19 patients, we evaluated whether CD14 high CD16 cells represent a source of inflammasome activation during COVID-19

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