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GHK-Cu has a 1,000,000-fold window between observed effect and toxicity, which is one reason injectable forms have been used compounded under prescription for decades without major safety signals

Safety Notes Both options have strong safety profiles when used appropriately: GHK-Cu topical is typically non-irritating for most people

Alpha GPC at 300 to 600 mg per day or CDP-Choline at 250 to 500 mg per day are the most bioavailable sources and are the standard companion to any racetam protocol

Potential long-term effects of nootropic supplementation are also still unknown

DMEM/F12 was used as a control for background luminescence